Projects:

 

* Advanced synthetic bone graft development program

* Advanced anti-bacteria coating on the dental implant to prevent Peri-Implantitis

 

 

* Advanced synthetic bone graft development program       

Bone graft materials have been developed for over decades. The current available products come in different composition, shape, size and sources, as indicated in the following pictures.

Over 90% of the bone graft markets were dominated by spinal and orthopaedic application. Therefore, most of the advanced bone graft development usually excluded dental applications.  

However, as the dental implant procedure becomes more popular amongst the aging population, the demand for high quality bone graft materials is on the rise in order to meet the dental implant requirements.  

The ideal dental bone graft should be able to achieve fast bone remodelling, high mechanical strength and well vascularized bone graft sites. The dentist will then be able to place the dental implant as soon as possible. The well-organised bone graft site will ensure successful dental implant integration.  

Traditional dental bone grafts are usually converted from animal bone, allograft (cadaver bone) or generic synthetic Calcium Phosphate granules. The main problem for these products is that there is no adequate porosity for osteoingrowth. The new bone formation is usually only limited on the surface of the granules. The graft site is almost like a brick wall being held together by a thin layer of cement, where the granules are the bricks and new bone formation is the thin layer of cement. Such composite structure is a particularly poor environment for the vascularization. Although the bone graft site feels solid without proper vascularization to supply the nutrient, the osteointegration of the dental implant just won't happen. Sometimes it will lead to implant failure.  

 

The following pictures show the typical new bone formation within the traditional dental bone graft granules. As you can see, the new bone formation is only between the granules and without organized vascularization in place.

To solve the problem, a new advanced dental bone graft was developed to solve the osteoingrowth and vascularization problem, as demonstrated in the following picture.

With such quick osteointegration and bone remodelling in just a few weeks, the proposed new dental bone graft could change the way how dentists perform the routine bone augmentation and dental implant procedure. The proposed dental bone graft will also be developed into putty form to aid the easy handling characteristics. The following picture shows the proposed dental bone graft putty performing the same as it was in granule form.

The proposed dental bone graft development program will combine with Anker Implant commercial activity; i.e. when the dentists adopt the Anker implant system, they will automatically share the progress of this new product development.

 

 

* Advanced anti-bacteria coating on the dental implant to prevent Peri-Implantitis

Peri-implantitis is an inflammatory disease marked by bacterial infection and the gradual loss of support from the jaw-bone to the implant. It’s not yet clear whether the infection causes the bone to recede, or whether the bone loss exposes the area to bacteria. Now it has been described as a “time bomb”.

The aim of the project is to develop a special coating for the dental implant to actively kill the bacteria to prevent peri-implantitis. Although the majority of patients do not have such problems, it is on the rise. Some studies and surveys even suggest that one third of patients will be infected.

Therefore, the special anti-bacterial coating will provide the reassurance for the patient and the dentist for the long term survivability of the dental implant without the peri-implantitis ever taking place.

The coating is not a thin layer of anti-bacterial material covering the whole surface of the implant, since it might hinder the osteointegration. Instead, the anti-bacterial material will form as scattered islands on the implant surface to kill the bacteria; this will not prevent osteointegration.

The coating materials and method are under development and will be part of the Anker Implant UK commercial activity so when dentists adopt the Anker implant system, they will automatically share the progress of this new developing technology.